Active B Complex

A wide and complex variety of B vitamins is essential for the body to convert food into cellular energy.

Remedy Active B Complex is formulated with eight essential B vitamins in their activated methylated forms, choline, inositol, and folate to support energy production, immune, cardiovascular and neurological health.‍

FOLATE

Folate is a member of the B complex vitamins that is critical for maintaining optimal methylation. Folate is found naturally in foods such as fruits and dark leafy vegetables, but can be easily destroyed by cooking or processing.

Additionally, enzyme defects, malabsorption and congenital deficiency of 5-methylenetetrahydrofolate reductase (5-MTHFR), an enzyme required for the conversion of folic acid to its bioactive form 5-methyltetrahydrofolate (5-MTHF), can result in an impaired ability to activate folic acid. In individuals with a genetic defect of this enzyme, supplementation with 5-MTHF has been shown to be beneficial.

5-MTHF is required for the production of mood regulating neurotransmitters such as serotonin, the synthesis of melatonin, as well as DNA production and repair.

5-MTHF also helps convert B12 (cobalamin) to methylcobalamin. Methylcobalamin helps convert the amino acid metabolite homocysteine into the amino acid methionine. Consistent recycling of homocysteine is vital to supporting cardiovascular and arterial health.

THIAMINE (VITAMIN B1)

While naturally abundant in whole grains, thiamine is lost in many of the over-processed grains commonly consumed today. Thiamine is essential for energy production, and is also needed for the metabolism of fats, proteins and carbohydrates. A recent study found that supplementation with high-dose thiamine supports blood sugar balance.

RIBOFLAVIN (VITAMIN B2)

Riboflavin is a precursor to flavin adenine dinucleodtide (FAD) and flavin mononucleotide (FMN), both of which are central to energy production, metabolism, and act as powerful antioxidants.

Riboflavin-depleted cells have been found to display signs of greater oxidative stress and disrupted energy generation. Studies have also shown that optimal riboflavin status has been found to help maintain already within normal range in patients with certain genetic predispositions.

NIACIN

Niacin helps with cellular energy production. In the body, niacin is transformed into NAD (Nicotinamide adenine dinucleotide) and NADP (Nicotinamide adenine dinucleotide phosphate), which both act as antioxidants.

Niacin or nicotinic acid has a long history of use in cardiovascular health, having been shown in numerous studies to support endothelial health.

VITAMIN B6

Vitamin B6 is involved in over 100 enzymatic reactions in the body and is essential for glucose metabolism, fat metabolism, neurotransmitter formation, immune health, hormone modulation, immune function, and is essential in methylation, for the breakdown of homocysteine.

A large study found that women who consumed, on average, 4.6 mg of vitamin B6 daily had significantly better markers of cardiovascular health compared to women who consumed an average of 1.1 mg daily.

VITAMIN B12

Vitamin B12, found only in organ meats, seafood and egg yolks, often becomes deficient in vegan and vegetarian diets. The vitamin is essential for the metabolism of fats and carbohydrates, the synthesis of proteins, and also plays a role in regulating mitochondrial enzymes and energy metabolism, as well as neurological health.

In a population study of 700 women aged 65 and over, more optimal B12 levels were found to be associated with better mood balance and health.

BIOTIN

Synthesized by the bacteria in the gut in addition to certain foods, biotin and its cofactors are involved in metabolism of fatty acids, amino acids, utilization of B vitamins and has been shown to support healthy blood sugar levels.

PANTOTHENIC ACID

Pantothenic acid and its biologically active derivative, CoA, are essential to the synthesis of fatty acids, membrane phospholipids, amino acids, steroid hormones, and energy production. 95% of CoA is found in the mitochondria.

Pantothenic acid has also been shown to have a balancing effect on blood fats and has also been shown in the research to support wound healing.

CHOLINE BITARTRATE

Though not technically a B vitamin, choline is often associated with B-vitamins. It is important in the construction of cell membranes and plasma lipoproteins, plays a role in cell signaling and in the synthesis of acetylcholine (a neurotransmitter), and is vital for brain development.

1 or more capsules per day.